Rejuran Dosage in Korea

December 28, 2025

Rejuran (often called Rejuran Healer) is one of Korea’s most popular PN/PDRN skin boosters for improving skin regeneration, texture, elasticity, and barrier repair. Dermatologists tailor the dosage based on the area treated, skin condition, and treatment goals.

Below is a clear, clinic-style guide to how Rejuran dosage works in Korea — how much is typically used, where it’s injected, and how many sessions are recommended.

1. What Rejuran Does

Rejuran contains polynucleotides (PN/PDRN), which support skin repair and collagen stimulation. It’s commonly used for:

  • Aging skin (fine lines, elasticity loss)
  • Rough texture
  • Sensitive or damaged skin
  • Post-laser or post-treatment care

Instead of adding volume like filler, Rejuran works by improving skin biology from the inside out.

2. Common Dosage by Area

Dosage varies by clinic and individual assessment, but in Korea, typical treatment amounts are as follows:

AreaTypical Volume per SessionFull Face~2.0–2.5 mLUnder-Eye / Tear Trough~0.5–1.0 mL per eyeNeck~1.5–2.5 mLDécolletage~1.5–3.0 mLHands~1.0–2.0 mLLocalized Concerns (scars, texture)~0.5–1.5 mL

Dosage may be adapted depending on skin thickness, severity of concerns, and the clinician’s protocol.

3. Injection Technique & Depth

Rejuran is typically injected into the dermis or superficial subdermal layer using:

  • Microdroplet technique for even distribution
  • Linear threading for broader coverage
  • A fine needle or cannula depending on area and sensitivity

Clinics may apply topical numbing to ensure comfort.

4. How Many Sessions & Frequency

Typical Session Plan (Korea)

  • Initial Course:
    → 3 sessions spaced 3–4 weeks apart
  • Maintenance:
    → 1 session every 3–6 months after initial course

Most patients notice gradual improvements after the first or second session, with more visible texture and elasticity changes after the third session.

5. What to Expect After Treatment

  • 0–3 days: Mild redness, swelling, or tiny bumps possible
  • 3–7 days: Calm, hydrated skin begins to appear
  • Week 3–6: Collagen stimulation becomes more noticeable
  • Week 8–12+: Fuller improvement in texture and elasticity

Downtime is typically minimal, allowing patients to return to daily activities quickly.

6. Why Dosage Matters

  • Using too little can limit the regenerative effect.
  • Using too much or injecting too deep can cause bumps or uneven texture.
  • Experienced injectors tailor dose + depth + spacing for natural results.

7. Combination Strategies in Korea

Korean clinics often combine Rejuran with:

  • Laser toning or fractional lasers for texture + clarity
  • RF or HIFU for tightening
  • Hydration boosters for extra radiance

Combined protocols can enhance overall results.

Summary

In Korea, Rejuran dosage is typically:

  • ~2.0–2.5 mL for full face
  • ~0.5–1.0 mL per under-eye
  • Multiple sessions spaced 3–4 weeks apart
  • A maintenance plan every few months afterward

This approach ensures gradual skin regeneration, improved texture, and sustained elasticity improvements.

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